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QUESTIONS

How much weight can I lose on semaglutide or tirzepatide?

HomeQuestionsPrimary CareMedical Weight LossHow much weight can I lose on semaglutide or tirzepatide?

Quick Answer

In clinical trials, patients on semaglutide (Wegovy) lost an average of about 15% of body weight at 68 weeks, and patients on tirzepatide (Zepbound) lost an average of about 20% of body weight at 72 weeks. Real-world results vary — patients who combine medication with lifestyle changes (nutrition, activity, sleep) typically see the strongest results. We set honest expectations during your first visit.

This question comes up frequently for patients researching medical weight loss at Good Health NC in Knightdale, NC.

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