Quick Answer
Yes — TMS has strong evidence for major depressive disorder, particularly in patients who haven't responded to antidepressants. Published response rates in treatment-resistant depression run roughly 50–60%, with remission rates around 30–40%. Most patients who respond notice change in the second half of the typical 36-session course. TMS is FDA-cleared and recommended in standard depression treatment guidelines for patients who haven't responded to medication.
This question comes up frequently for patients researching tms therapy for depression at Good Health NC in Knightdale, NC.